Monday, June 25, 2012

Herbs for Diabetes


Pterocarpus marsupium (Indian Kino, Malabar Kino, Pitasara, Venga)

The tree is the source of the Kino of the European pharmacopeas. The gum-resin looks like dried blood (Dragon's blood), much used in Indian medicine. This herb has a long history of use in India as a treatment for diabetes. The flavonoid, (-)-epicatechin, extracted from the bark of this plant has been shown to prevent alloxan-induced beta cell damage in rats.

Both epicatechin and a crude alcohol extract of Pterocarpus marsupium have actually been shown to regenerate functional pancreatic beta cells. No other drug or natural agent has been shown to generate this activity.


Bitter Melon (Momordica charantia)

Bitter melon, also known as balsam pear, is a tropical vegetable widely cultivated in Asia, Africa and South America, and has been used extensively in folk medicine as a remedy for diabetes. The blood sugar lowering action of the fresh juice or extract of the unripe fruit has been clearly established in both experimental and clinical studies.

Bitter melon is composed of several compounds with confirmed anti-diabetic properties. Charantin, extracted by alcohol, is a hypoglycaemic agent composed of mixed steroids that is more potent than the drug tolbutamide which is often used in the treatment of diabetes. Momordica also contains an insulin-like polypeptide, polypeptide-P, which lowers blood sugar levels when injected subcutaneously into type 1 diabetic patients. The oral administration of 50-60 ml of the juice has shown good results in clinical trials.

Excessively high doses of bitter melon juice can cause abdominal pain and diarrhea. Small children or anyone with hypoglycemia should not take bitter melon, since this herb could theoretically trigger or worsen low blood sugar, or hypoglycemia. Furthermore, diabetics taking hypoglycemic drugs (such as chlorpropamide, glyburide, or phenformin) or insulin should use bitter melon with caution, as it may potentiate the effectiveness of the drugs, leading to severe hypoglycemia.


Gymnema Sylvestre (Gurmar, Meshasringi, Cherukurinja)

Gymnema assists the pancreas in the production of insulin in Type 2 diabetes. Gymnema also improves the ability of insulin to lower blood sugar in both Type 1 and Type 2 diabetes. It decreases cravings for sweet. This herb can be an excellent substitute for oral blood sugar-lowering drugs in Type 2 diabetes. Some people take 500 mg per day of gymnema extract.


Onion and Garlic ( Allium cepa and Allium sativum)

Onion and garlic have significant blood sugar lowering action. The principal active ingredients are believed to be allyl propyl disulphide (APDS) and diallyl disulphide oxide (allicin), although other constitutents such as flavonoids may play a role as well. 
Experimental and clinical evidence suggests that APDS lowers glucose levels by competing with insulin for insulin-inactivating sites in the liver. This results in an increase of free insulin. APDS administered in doses of 125 mg/ kg to fasting humans was found to cause a marked fall in blood glucose levels and an increase in serum insulin. Allicin doses of 100 mg/kg produced a similar effect. 

Onion extract was found to reduce blood sugar levels during oral and intravenous glucose tolerance. The effect improved as the dosage was increased; however, beneficial effects were observed even for low levels that used in the diet (eg., 25 to 200 grams). The effects were similar in both raw and boiled onion extracts. Onions affect the hepatic metabolism of glucose and/or increases the release of insulin, and/or prevent insulin's destruction. 

The additional benefit of the use of garlic and onions are their beneficial cardiovascular effects. They are found to lower lipid levels, inhibit platelet aggregation and are antihypertensive. So, liberal use of onion and garlic are recommended for diabetic patients. 


Fenugreek (Trigonella foenum-graecum) 

Experimental and clinical studies have demonstrated the antidiabetic properties of fenugreek seeds. The active ingredient responsible for the antidiabetic properties of fenugreek is in the defatted portion of the seed that contains the alkaloid trogonelline, nicotinic acid and coumarin. 


Blueberry leaves (Vaccinium myrtillus) 

A decoction of the leaves of the blueberry has a long history of folk use in the treatment of diabetes. The compound myrtillin (an anthocyanoside) is apparently the most active ingredient. Upon injection it is somewhat weaker than insulin, but is less toxic, even at 50 times the 1 g per day therapeutic dose. A single dose can produce beneficial effects lasting several weeks.

Blueberry anthocyanosides also increase capillary integrity, inhibit free-radical damage and improve the tone of the vascular system. In Europe, it is used as an anti-haemorrhagic agent in the treatment of eye diseases including diabetic retinopathy. 


Asian Ginseng

Asian ginseng is commonly used in traditional Chinese medicine to treat diabetes. It has been shown to enhance the release of insulin from the pancreas and to increase the number of insulin receptors. It also has a direct blood sugar-lowering effect.
A recent study found that 200 mg of ginseng extract per day improved blood sugar control as well as energy levels in Type 2 diabetes (NIDDM).


Bilberry

Bilberry may lower the risk of some diabetic complications, such as diabetic cataracts and retinopathy. 


Stevia

Stevia has been used traditionally to treat diabetes. Early reports suggested that stevia might have beneficial effects on glucose tolerance (and therefore potentially help with diabetes), although not all reports have confirmed this. Even if stevia did not have direct antidiabetic effects, its use as a sweetener could reduce intake of sugars in such patients.


Ginkgo Biloba

Ginkgo biloba extract may prove useful for prevention and treatment of early-stage diabetic neuropathy.

Cinnamon -  Triples insulin's efficiency

Barberry - One of the mildest and best liver tonics known.
Dosage: tincture, 10-30 drops; standard decoction or 3-9 g.


Herbal Combinations

For all pancreatic problems:
1 part uva ursi
1 part goldenseal
1 part elecampane
2 parts dandelion root
2 parts cedar berries
1 part fennel part ginger 
Mix the powdered herbs and put them in #00 capsules. Take them after every meal. 

Vitamins for Diabetes


Vitamin E

People with diabetes have a higher than usual need for vitamin E, which improves insulin activity and acts as an antioxidant and a blood oxygenator. Research has shown that people with low blood levels of vitamin E are more likely to develop Type 2 diabetes. Double-blind studies show that vitamin E improves glucose tolerance in people with Type 2 diabetes (NIDDM). Vitamin E was found to improve glucose tolerance in elderly non-diabetics.

A vitamin E deficiency results in increased free-radical-induced damage, particularly of the lining of the vascular system. Supplemental vitamin E may help prevent diabetic complications through its antioxidant activity, the inhibition of the platelet-releasing reaction and platelet aggregation, increasing HDL-cholesterol levels and its role in fatty acid metabolism. Vitamin E protects animals from diabetic cataracts. 

The most impressive study on vitamin E and diabetes used a total of 1,350 international units of d-alpha-tocopheryl acetate daily, divided into three doses. Begin by taking 400 international units each morning. After two weeks, add another dose of 400 international units in the evening. After two more weeks, add another 400 international units in the afternoon.

It may require three months or more of supplementation for benefits to become apparent. The trace mineral selenium functions synergistically with vitamin E.
Note: If you have high blood pressure, limit your intake of supplemental vitamin E to a total of 400 international units daily. If you are taking an anticoagulant (blood thinner), consult your physician before taking supplemental vitamin E. 


Vitamin C

People with Type 1 diabetes (IDDM) have low vitamin C levels. Vitamin C lowers sorbitol in diabetics. Sorbitol is a sugar that can accumulate and damage the eyes, nerves, and kidneys of diabetics. Vitamin C may improve glucose tolerance in Type 2 diabetes (NIDDM).

The transport of vitamin C into cells is facilitated by insulin. It has been postulated that, due to impaired transport or dietary insufficiency, a relative vitamin C deficiency exists in the diabetic and that this may be responsible for the increased capillary permeability and other vascular disturbances seen in diabetics.

If you are diabetic, supplement your diet with 1-3 grams per day of vitamin C.


Vitamin B6 (Pyridoxine)

Diabetics with neuropathy have been shown to be deficient in vitamin B6 and benefit from supplementation. Peripheral neuropathy is a known result of pyridoxine deficiency and is indistinguishable from diabetic neuropathy. Vitamin B6 supplements improve glucose tolerance in women with diabetes caused by pregnancy. Vitamin B6 is also effective for glucose intolerance induced by the birth control pill. 1,800 mg per day of a special form of vitamin B6-pyridoxine alpha-ketoglutarate-improves glucose tolerance dramatically.

Pyridoxine is also important in preventing other diabetic complications because it is an important coenzyme in the cross-linking of collagen and inhibits platelet aggregation.


Vitamin B12

Vitamin B12 supplementation has been used with some success in treating diabetic neuropathy. It is not clear if this is due to the correcting of a deficiency state or normalizing vitamin B12 metabolism.

Vitamin B12 is needed for normal functioning of nerve cells. Vitamin B12 taken orally, intravenously, or by injection reduces nerve damage caused by diabetes in most people.
Oral supplementation may be sufficient, but intramuscular vitamin B12 may be necessary in many cases. Take up to 500 mcg of Vitamin B12 three times per day. 


Biotin

Biotin is a B vitamin needed to process glucose. It has been shown to work synergistically with insulin and independently in increasing the activity of glucokinase. This enzyme is responsible for the first step in glucose utilization. Glucokinase is present only in the liver, where, in diabetics, its concentration is very low.

Supplementation with large quantities of biotin may significantly enhance glucokinase activity, thereby improving glucose metabolism in diabetics. When people with Type 1 diabetes (IDDM) were given 16 mg of biotin per day for just one week, their fasting glucose levels dropped by 50%. Similar results have been reported using 9 mg per day for two months in people with Type 2 diabetes (NIDDM). Biotin may also reduce pain from diabetic nerve damage.

Take 16 mg of biotin for a few weeks to see if blood sugar levels will fall.


Niacin

High levels-several grams per day-of niacin, a form of vitamin B3, impair glucose tolerance . So, avoid it if you are diabetic. Smaller amounts (500-750 mg per day for one month followed by 250 mg per day) of niacin may help some people with Type 2 diabetes (NIDDM).


Chromium

As a key constituent of the 'glucose tolerance factor,' chromium is a critical nutrient in diabetes. Supplementation in the form of chromium chloride (200 micro g daily) or high-chromium-containing brewer's yeast (9 g a day) has been demonstrated to decrease fasting glucose levels, improve glucose tolerance, lower insulin levels and decrease total cholesterol and triglyceride levels, while increasing HDL-cholesterol levels.

Double-blind research shows that chromium supplements improve glucose tolerance in people with both Type 1 and Type 2 diabetes, apparently by increasing sensitivity to insulin. Chromium improves the processing of glucose in people with pre-diabetic glucose intolerance and in women with diabetes associated with pregnancy.

The typical amount of chromium used in research trials is 200 mcg per day. Some doctors recommend up to 1,000 mcg per day of Chromium for diabetics.
Niacin administered at relatively low levels (100 mg) along with 200 mcg of chromium has been shown to be more effective than chromium alone. Exercise increases tissue chromium concentrations.


Manganese

Manganese is an important cofactor in the key enzymes of glucose metabolism. A deficiency of manganese was found to result in diabetes in guinea pigs. It also resulted in the frequent birth of offspring who develop pancreatic abnormalities or no pancreas at all. Diabetics have been shown to have only one-half the manganese of normal individuals.


Magnesium

Magnesium levels are significantly lowered in diabetics, and lowest in those with severe retinopathy. Studies suggest that a deficiency in magnesium may worsen the blood sugar control in Type 2 diabetes. Scientists believe that a deficiency of magnesium interrupts insulin secretion in the pancreas and increases insulin resistance in the body's tissues. 

Studies suggest that a deficiency in magnesium may worsen the blood sugar control in Type 2 diabetes. Scientists believe that a deficiency of magnesium interrupts insulin secretion in the pancreas and increases insulin resistance in the body's tissues. 

Supplementation with magnesium leads to improved insulin production in elderly people with Type 2 diabetes. Elders without diabetes may also produce more insulin as a result of magnesium supplements. Insulin requirements are lower in people with Type 1 diabetes who supplement with magnesium.

Diabetes-induced damage to the eyes is more likely to occur to magnesium-deficient people with Type 1 diabetes (IDDM). In pregnant women with IDDM who are magnesium deficient, the lack of magnesium may even account for the high rate of spontaneous abortion and birth defects associated with IDDM. Low magnesium levels appears to be a significant risk factor in the development of cardiovascular disease, particularly coronary artery spasm.

Many doctors of natural medicine recommend that diabetics with normal kidney function supplement with 300-400 mg of magnesium per day.


Vanadium

Vanadium is a compound found in tiny amounts in plants and animals. Early studies showed that vanadium normalized blood glucose levels in animals with Type 1 and Type 2 diabetes. A recent study found that when people with diabetes were given vanadium, they developed a modest increase in insulin sensitivity and were able to decrease their insulin requirements. 


Potassium

Potassium supplementation yields improved insulin sensitivity, responsiveness and secretion in diabetics. Insulin administration often causes a potassium deficiency.


Zinc

Zinc deficiency has been suggested to play a role in the development of diabetes in humans. Zinc is involved in virtually all aspects of insulin metabolism -synthesis, secretion and utilization. Zinc also has a protective effect against beta cell destruction, and has well-known anti-viral effects.

People with Type 1 diabetes (IDDM) tend to be zinc deficient, which may impair immune function. Zinc supplements have lowered blood sugar levels in people with IDDM. People with Type 2 diabetes (NIDDM) also have low zinc levels, caused by excess loss of zinc in their urine.

People with NIDDM are recommended to supplement their diet with moderate amounts of zinc (15-50 mg per day) as a way to correct for the deficit.
Note: Take zinc with food to prevent stomach upset. If you take over 30 milligrams of zinc on a daily basis for more than one or two months, you should also take 1 to 2 milligrams of copper each day to maintain a proper mineral balance.


Coenzyme Q10

People with diabetes cannot adequately process carbohydrates. Coenzyme Q10, or CoQ10, is needed for normal carbohydrate metabolism. Coenzyme Q10 is an antioxidant that fights free-radical damage and is a blood oxygenator.

Animals with diabetes are CoQ10 deficient. In one trial, blood sugar levels fell substantially in 31% of people with diabetes after they supplemented with 120 mg of CoQ10 per day.
Because the eye is so richly supplied with tiny blood vessels, this is another nutrient that can help in cases of retinopathy. Take 50 milligrams of coenzyme Q10 twice daily for up to three months, then reduce the dosage to 30 milligrams daily.


Inositol

Inositol is needed for normal nerve function. Diabetes can cause nerve damage, or diabetic neuropathy. Some of these abnormalities have been reversed by inositol supplementation (500 mg taken twice per day).


ALA and GLA

Alpha-lipoic acid (ALA) is a powerful natural antioxidant. It has been used to improve diabetic neuropathies (at an intake of 600 mg per day) and has reduced pain in several studies.

Gamma-linolenic acid (GLA), found in black currant seed oil, borage oil, and evening primrose oil, has been shown to be helpful for improving damaged nerve function, which is common in diabetes.

Supplementing with 4 grams of evening primrose oil per day for six months has been found to reverse the cause of diabetic nerve damage and improve this painful condition. In double-blind research, 6 grams per day helps reduce nerve damage in people with both Type 1 and Type 2 diabetes (IDDM and NIDDM).

Take 500 to 1,000 milligrams of any of these oils twice daily.


Carnitine

Carnitine is a substance needed for the body to properly use fat for energy. When diabetics are given carnitine (1 mg per 2.2 pounds of body weight), high blood levels of fats-both cholesterol and triglycerides-dropped 25-39% in just ten days. In addition, carnitine improves the breakdown of fatty acids, possibly playing a role in preventing diabetic ketoacidosis.


Taurine

Taurine is an amino acid found in protein-rich food. People with Type 1 diabetes (IDDM) have low taurine levels, that leads to "thickened" blood-a condition which increases the risk of heart disease. Supplementing taurine (1.5 grams per day) restores taurine levels to normal and corrects the problem of blood viscosity within three months. 

Thursday, June 21, 2012

the food cycle


Projections are that over 50% of the US population will have some form of diabetes by 2014.

The government subsidizes buying cheep genetically modified corn from giant corporate growing operations, it then becomes a cheep ingredient in the vast majority of processed foods on grocery store shelves, and then we wonder why more and more people have problems with obesity and diabetes.

On the other side, treatment of diabetes with quarterly doctor visits, pharmaceutical drugs, medical equipment (needles, blood sugar monitors, and test strips) is big big $$.

Next time you are out shopping, start looking at the ingredients of all the (relatively) lower cost foods.

Anything fresh and healthy costs outrageous, while anything with HCFS is cheep.

What better way to keep lower income folks sick, dependent, and weak so they cannot fight back.